3D Phase-Field Simulations Explain Experimental Observations of Structure Formation in Ice-Templated Materials

Freeze casting is a promising processing technique that provides a means to mimic natural materials with hierarchical designs over several length-scales with biomedical applications. Directional solidification of ceramic-based suspensions in water. 3D quantitative phase-field simulation with massive parallel computing at the experimentally relevant time and length scales. Objective and Approach: Qualitative comparisons between phase-field simulations and freeze casting experiments to understand top hierarchical levels in the freeze-cast material

Joint Diagonalization Applied to the Detection and Discrimination of Unexploded Ordnance

Efforts to discriminate buried unexploded ordnance from harmless surrounding clutter are often hampered by the uncertainty in the number of buried targets that produce a given detected signal. We present a technique that helps determine that number with no need for data inversion. The procedure is based on the joint diagonalization of a set of multistatic response (MSR) matrices measured at different time gates by a time-domain electromagnetic induction sensor. In particular, we consider the Naval Research Laboratory’s Time-Domain Electromagnetic Multisensor Towed Array Detection System (TEMTADS), which consists of a 5×5 square grid of concentric transmitter/receiver pairs. The diagonalization process itself generalizes one of the standard procedures for extracting the eigenvalues of a single matrix; in terms of execution time, it is comparable to diagonalizing the matrices one by one. We present the method, discuss and illustrate its mathematical basis and physical meaning, and apply it to several actual measurements carried out with TEMTADS at a test stand and in the field at the former Camp Butner in North Carolina. We find that each target in a measurement is associated with a set of nonzero time-dependent MSR eigenvalues (usually three), which enables estimation of the number of targets interrogated. These eigenvalues have a characteristic shape as a function of time that does not change with the location and orientation of the target relative to the sensor. We justify analytically and empirically that symmetric targets have pairs of eigenvalues with constant ratios between them

Characterization of an Implicitly Resistively-Loaded Monopole Antenna in Lossy Liquid Media

Abstract Microwave tomographic imaging of the breast for cancer detection is a topic of considerable interest because of the potential to exploit the apparent high-dielectric property contrast between normal and malignant tissue. An important component in the realization of an imaging system is the antenna array to be used for signal transmission/detection. The monopole antenna has proven to be useful in our implementation because it can be easily and accurately modeled and can be positioned in close proximity to the imaging target with high-element density when configured in an imaging array. Its frequency response is broadened considerably when radiating in the liquid medium that is used to couple the signals into the breast making it suitable for broadband spectral imaging. However, at higher frequencies, the beam patterns steer further away from the desired horizontal plane and can cause unwanted multipath contributions when located in close proximity to the liquid/air interface. In this paper, we have studied the behavior of these antennas and devised strategies for their effective use at higher frequencies, especially when positioned near the surface of the coupling fluid which is used. The results show that frequencies in excess of 2 GHz can be used when the antenna centers are located as close as 2 cm from the liquid surface

Fabrication of monodisperse magnetic nanorods for improving hyperthermia efficacy

Background: Hyperthermia is one of the promising cancer treatment strategies enabled by local heating with the use of tumor-targeting magnetic nanoparticles (MNP) under a non-invasive magnetic field. However, one of the remaining challenges is how to achieve therapeutic levels of heat (without causing damages to regular tissues) in tumors that cannot be effectively treated with anti-tumor drug delivery. Results: In this work, we report a facile method to fabricate magnetic nanorods for hyperthermia by one-step wet chemistry synthesis using 3-Aminopropyltrimethoxysilane (APTMS) as the shape-controlling agent and ferric and ferrous ions as precursors. By adjusting the concentration of APTMS, hydrothermal reaction time, ratios of ferric to ferrous ions, magnetic nanorods with aspect ratios ranging from 4.4 to 7.6 have been produced. At the clinically recommended field strength of 300 Oe (or less) and the frequency of 184 kHz, the specific absorption rate (SAR) of these nanorods is approximately 50 % higher than that of commercial Bionized NanoFerrite particles. Conclusions: This increase in SAR, especially at low field strengths, is crucial for treating deep tumors, such as pancreatic and rectal cancers, by avoiding the generation of harmful eddy current heating in normal tissues.[Figure not available: see fulltext.

Surface Wave Multipath Signals in Near-Field Microwave Imaging

Microwave imaging techniques are prone to signal corruption from unwanted multipath signals. Near-field systems are especially vulnerable because signals can scatter and reflect from structural objects within or on the boundary of the imaging zone. These issues are further exacerbated when surface waves are generated with the potential of propagating along the transmitting and receiving antenna feed lines and other low-loss paths. In this paper, we analyze the contributions of multi-path signals arising from surface wave effects. Specifically, experiments were conducted with a near-field microwave imaging array positioned at variable heights from the floor of a coupling fluid tank. Antenna arrays with different feed line lengths in the fluid were also evaluated. The results show that surface waves corrupt the received signals over the longest transmission distances across the measurement array. However, the surface wave effects can be eliminated provided the feed line lengths are sufficiently long independently of the distance of the transmitting/receiving antenna tips from the imaging tank floor. Theoretical predictions confirm the experimental observations

Characterization of an Implicitly Resistively-Loaded Monopole Antenna in Lossy Liquid Media

Microwave tomographic imaging of the breast for cancer detection is a topic of considerable interest because of the potential to exploit the apparent high-dielectric property contrast between normal and malignant tissue. An important component in the realization of an imaging system is the antenna array to be used for signal transmission/detection. The monopole antenna has proven to be useful in our implementation because it can be easily and accurately modeled and can be positioned in close proximity to the imaging target with high-element density when configured in an imaging array. Its frequency response is broadened considerably when radiating in the liquid medium that is used to couple the signals into the breast making it suitable for broadband spectral imaging. However, at higher frequencies, the beam patterns steer further away from the desired horizontal plane and can cause unwanted multipath contributions when located in close proximity to the liquid/air interface. In this paper, we have studied the behavior of these antennas and devised strategies for their effective use at higher frequencies, especially when positioned near the surface of the coupling fluid which is used. The results show that frequencies in excess of 2 GHz can be used when the antenna centers are located as close as 2 cm from the liquid surface

Mechanisms of Structure Formation in Ice-Templated Materials Experimental Observations

No abstract availabl